The Colorado Department of Transportation is urging drivers to leave work early Tuesday if they can.
Monday night, CDOT issued a warning about the impending storm that is expected to arrive Tuesday and last into midday Wednesday.
Record-breaking cold temperatures and significant accumulation is expected in many areas.
The National Weather Service has the entire Denver metro area under a winter storm warning from Tuesday morning to Wednesday evening.
Both Tuesday and Wednesday are Pinpoint Weather Alert Days.
Anywhere from 10 to 12 inches of snow are possible by midday Wednesday after a storm on Sunday night and Monday morning left up to 7 inches of snow in some areas near downtown Denver.
Source: FOX 31